Colorado Serum Tetanus Antitoxin, 10 x 1,500 Units

Ten 5 mL doses of Colorado Serum Tetanus Antitoxin, labeled for cattle, sheep, goats, and swine. The manufacturer says not to use in equine species.

Antitoxin for labeled livestock species

Colorado Serum Tetanus Antitoxin is a veterinary biologic supplied in a package of ten individual doses. Each 5 mL dose contains 1,500 units. The manufacturer lists cattle, sheep, goats, and swine as the labeled species and explicitly says not to use in equine species. That species limit is central to choosing this product. It is not a horse vaccine or a horse antitoxin. A horse owner needing tetanus protection should ask a veterinarian for a product labeled for horses. The manufacturer describes tetanus antitoxin as an aid in prevention and treatment of tetanus in animals. It recommends use when a non-immunized animal has a deep wound that may have been contaminated with soil, including situations after castration or docking and other circumstances where tetanus has been a problem. The manufacturer notes that the exact duration of passive immunity is unknown, although literature states 7 to 14 days, and that safety in pregnant animals is unknown. A veterinarian should assess the animal and select the labeled use and dose. For prevention, the manufacturer lists 1,500 units, or 5 mL, given subcutaneously or intramuscularly. Its treatment guidance specifies 10,000 to 50,000 units for cattle and 3,000 to 15,000 units for sheep and swine. The manufacturer cautions that large doses may provide a beneficial response in animals already infected with tetanus, but treatment success is not assured. It also describes a second dose after seven days for animals with slow-healing puncture wounds or deep abrasions, with further doses as considered necessary. Read the current product directions and consult a veterinarian before use. Keep the package refrigerated at 2–8°C and do not freeze. Shake well before use, use the entire contents when first opened, and do not mix with other products. The label says not to vaccinate within 21 days before slaughter. It also warns that anaphylactoid reactions may occur and that some individuals may be allergic to equine serum proteins. The product contains phenol and thimerosal preservatives. Keep the carton and vial labels together so the strength, lot, expiry, species restriction, and storage details stay with the product.

Manufacturer product details and label directions

Colorado Serum Company Tetanus Antitoxin, catalog item 13603. Retail package: ten 5 mL doses, 1,500 units per dose; UPC 009252136031. The current manufacturer page lists cattle, sheep, goats and swine and explicitly states not to use in equine species. Contains phenol and thimerosal preservatives.

Directions for use

Store at 2–8°C. DO NOT FREEZE. Do not vaccinate within 21 days before slaughter. Shake well before use. Use entire contents when first opened. Do not mix with other products. Do not use in equine species. 1,500 units (5 ml) administered subcutaneously or intramuscularly is the recommended preventive dose. 5 ml equals 1,500 units. For treatment, administer 10,000 to 50,000 units to cattle, 3,000 to 15,000 units to sheep and swine. FOR TREATMENT: Large doses of Tetanus Antitoxin may provide beneficial response in animals already infected with tetanus, but success of treatment is not assured. Animals with slow healing puncture wounds or deep abrasions should be given a second dose of antitoxin in 7 days and additionally as deemed necessary. Consult a veterinarian for vaccination program.

Cautions

Do not use in equine species. Safety in pregnant animals is unknown. Anaphylactoid reaction may occur following administration of products of this nature. If noted, administer adrenalin or equivalent. In case of human exposure, consult a physician. Contains phenol and thimerosal as preservatives. Some individuals can be allergic to equine serum proteins and an allergic reaction is possible.